Is CBD Effective without THC?
CBD and THC Together
Scientific evidence suggests that as a therapeutic treatment, THC and CBD operate as power couple when ingested in combination. Both compounds have a significant impact on each other and works best together. When THC and CBD are combined as a treatment therapy, CBD acts as an inhibitor, prolonging the effects of THC-therapy, and may reduce the psycho-activity often associated with THC. Studies conducted at the California Pacific Medical Center in San Francisco have revealed that a combination of specific amounts of CBD and THC has a more potent anti-tumoral effect than either compound alone when tested on brain and breast cancer cell lines. Source https://www.projectcbd.org/article/cbd-misconceptions Further studies have also demonstrated that CBD and THC together, potentiates THC’s pain relieving properties in treating neuropathic pain, as well as its anti-inflammatory properties in an animal model of colitis.
Can CBD Offer Clinical Benefits in Absence of THC
The current trend in the reduction of THC content and the enhancement in the amount of CBD in cannabis or hemp treatment products is deliberate. It has been demonstrated that CBD-rich cannabis has the potential to produce considerable therapeutic effects. However, some scientists are curious to discover if CBD as a singular compound can be equally effective as CBD and THC combined. Based on a study, “Overcoming the Bell-Shaped Dose-Response of Cannabidiol by using Cannabis Extract Enriched in Cannabidiol,” conducted by the Hebrew University of Jerusalem that sought to compare the effectiveness of a completely purified CBD extract versus a full-spectrum extract of cannabis flowers containing large quantities of CBD, it was demonstrated that the whole plant extract proved far more effective than CBD-only solutions in ameliorating inflammation and pain. Source http://caregiversforlife.net/cannabis-study-full-spectrum-cannabis-extracts-more-medically-effective-than-cbd-alone/
This big question for scientist Gary Wenk, Professor of Psychology and Neuroscience and Molecular Virology, Immunology, and Medical Genetics at the Ohio State University and Medical Center: Is CBD capable of delivering any clinical benefits in the absence of other compounds, especially THC? Source https://healthyhempoil.com/is-cbd-effective/ Dr. Wenk is careful to point out to CBD enthusiasts that, while CB receptors-interacting protein in the brain serves as the contact points between marijuana and user, it is still unclear as to how the brain interacts with all the cannabis compounds directly because the system is a complex one. Not much detail is present that compares the effectiveness of one cannabis compound to another. Much of the research on cannabis has been of a general nature that involves the entire plant, and even when examining CBD, THC is almost always involved in the process.
Doctor Guillermo Velasco of Complutense University of Madrid in Spain, Professor Velasco, whose research focuses on cannabis and cancer, believes that it is important to have the whole plant as a medicine, and not simply CBD-only medicine. He stated, “In my opinion as a scientist, I’ve been working with [cannabis] for quite a long time. THC is the compound that has the most potent anti-cancer activity. CBD is helping—we tried a lot of combinations of THC and CBD because it’s good for avoiding the side effects of the therapy […] but, definitely THC is important.” Source https://www.leafly.com/news/health/how-effective-is-cbd-on-its-own
The general view based on research findings is that cannabidiol (CBD) and THC are more effective together. This theory largely stems from the fact that most studies have focused on a combination of CBD and THC, and not on the effectiveness of either compound separately, except for very few researches. CBD, when isolated from THC does not appear potent enough to have effective medicinal value. There is a need to understand how cannabinoids work and are processed in the body beyond interaction with CB receptors. Some scientists believe that it is more beneficial to examine the whole plant as a medicine. Whether or not CBD is fully effective on its own is still inconclusive; there is a need for more research.