At present, chemotherapy is one of the most practiced approaches for the treatment of advanced metastatic cervical cancer. However, clinical application of this approach often features serious challenges involving the development of chemoresistance and toxic side effects.
Thus, there is an urgent need to develop a new non-toxic modality for the prevention and treatment of cancer.
Cucurbitacins have potential to be used as possible bioactive agents for inhibiting cancer progression and these compounds contain structural improvements for future potential chemotherapeutic modalities.
Various studies have demonstrated that cucurbitacin analogues have a broad range of biological effects including anti-inflammatory, hepatoprotective, anticancer and antioxidant activities.
Pumpkin seeds are a great source of cucurbitacins.
German scientists also found that pumpkin seeds can be of great help for women in menopause when it comes to reducing the risk of breast cancer. Regular consumption of pumpkin seed reduced the risk of breast cancer by 23%.
Pumpkin seeds are rich in magnesium, manganese, copper, potassium, calcium, iron, phosphorus, selenium and other minerals. The fiber in pumpkin seeds enhances digestion, and the seeds also contain bioavailable protein.
Magnesium and zinc contribute to the absorption of nutrients, which is why pumpkin seeds are recommended to those who deal with health problems caused by nutrient deficiencies.
Pumpkin seeds also contain zinc, which can assist the brain in converting tryptophan into serotonin. In fact, pumpkin seed powder is the new ‘warm glass of milk’ when it comes to sleep remedies (this is available at most health food stores).
For a powerful evening snack mix ¼ cup of pumpkin seeds (or powder) with 1-2 tablespoons chia seeds and ¾ cup of unsweetened Greek yogurt.
Add pumpkin seeds to your daily menu to strengthen your immune system, lower your blood sugar, sleep well, improve your skin complexion and boost vision.
Zinc and phytosterols, especially beta-sitosterol prevent the development of abnormal prostate cancer cells. Their anti-inflammatory effect prevents oxidative damages, which promotes DNA repair and prevents cancer growth in the early stages of the disease.